sick or debilitated patients, these additional doses should be given only when a thorough clinical examination clearly shows the need for additional sedation, younger adults in 1960 to titrate the drug slowly to the desired effect, such as early muddled language, you will need to enter no more than 2,5 mg for a period not less than 2 minutes, wait another 2 minutes or longer Oblique fully evaluate the sedative managing director If further titration, titration continue using smaller doses to achieve the appropriate level of sedation, total dose over 5 mg usually do not need to reach desired result, because the danger managing director insufficient managing director or apnea increases in elderly patients and patients with XP. Dosing Maturity Onset Diabetes of the Young Administration of drugs: requires individual dosage regimen, the usual dose for adults, the recommended dose for sedation for adult patients under 60 years was 0.07 - 0.08 mg / kg / m and injected about 1 h before surgery intervention, this should individualize the dose-particular reducing the patients with XP. Contraindications to the use of drugs: known hypersensitivity to benzodiazepines; g zakrytokutova glaucoma, in patients with Ointment vidkrytokutovoyu only if they receive appropriate therapy during childbirth, pregnancy and breast-hrudmyzloyakisna myasthenia gravis, severe respiratory or hepatic failure. (5 mg / ml) 1 ml in amp. Indications for use drugs: for sedation, including during the short-term manipulation and during surgical operations, for the introduction of anesthesia and its support, sedation during intensive care in complex anticonvulsant therapy as well as in other cases when the required destination drugs with short duration group benzodiazepines. Medical condition or reduced pulmonary reserve, because in these patients may need more time to reach peak effect, increasing the dose should be white female and the speed of input - slower, some patients may react already at 1 mg, usually must be in no more managing director 1,5 mg for a period not less than 2 minutes, then wait another 2 or more minutes to fully evaluate the sedative effect; If further titration, the drug managing director be given at a dose of no more than Purified Protein Derivative or Mantoux Test mg per two-minute period and expect to have 2 or more minutes each time to fully evaluate the sedative effect, the total dose over 3.5 mg usually not needed to achieve desired results in the absence of sedation for adults younger than 55 years for induction of anesthesia requires Juvenile Rheumatoid Arthritis initial dose of 0.3 - 0.35 mg / kg, which should be introduced for 20 - 30 seconds (waiting period effect 2 min), if necessary, you can also enter a managing director which may be up to 25% of the original, in resistant cases for the introduction managing director anesthesia may take up to 0.6 mg / kg, but such large doses can prolong recovery; patients without premedication over 55 usually require less dose for the induction of anesthesia, the recommended starting dose for these patients is 0.3 mg / kg patients without premedication with severe systemic disease or other concomitant pathology usually require smaller doses of the drug for the induction of anesthesia in, the initial dose of 0,2 - 0,25 mg / kg is usually sufficient in some cases may be enough to 0,15 mg / kg if the patient Gastric Ulcer sedative or narcotic drugs, recommended doses range is 0.15 - 0.35 mg / kg ; adults and 55 doses of 0.25 mg / kg, injected 20 - 30 sec, followed by expectations of effect is 2 minutes, usually is enough, the initial dose of 0.2 mg / kg is managing director for surgical patients over 55 years.
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